Pregnant Women Have Lingering Depression Despite Medication


This is the primary examine to measure the completely different trajectories of melancholy and anxiousness in pregnant and postpartum girls. Through being pregnant, 18% of the ladies had minimal, 50% had delicate and 32% clinically related depressive signs.

“This is the first longitudinal data to show that many pregnant women report depression and anxiety symptoms during pregnancy and postpartum, despite their choice to continue treatment with antidepressants,” stated senior creator Dr. Katherine Wisner, director of the Asher Center for the Study and Treatment of Depressive Disorders and professor of psychiatry and of obstetrics and gynecology at Northwestern University Feinberg School of Medicine.

“It lets us know these women need to be continuously monitored during pregnancy and postpartum, so their clinicians can tailor their treatment to alleviate their symptoms.”

“Psychological and psychosocial factors change rapidly across childbearing,” stated co-author Dr. Catherine Stika, a medical professor of obstetrics and gynecology at Northwestern and a Northwestern Medicine gynecologist. “Repeated screenings will allow your clinician to adapt the type and/or intensity of intervention until your symptoms improve.”

Depression additionally impacts a lady’s toddler. “This is key as children exposed to a depressed mother have an increased risk of childhood developmental disorders,” Wisner stated.

The examine shall be revealed in Psychiatric Research and Clinical Practice.

The new analysis additionally confirmed that pregnant girls taking selective serotonin reuptake inhibitors to deal with their melancholy confirmed sub-optimal well being, together with elevated physique mass index, infertility, migraines, thyroid problems and bronchial asthma. A historical past of consuming problems predicted elevated melancholy trajectory scores.

Perinatal melancholy and anxiousness are widespread, affecting 20% โ€‹โ€‹of ladies throughout being pregnant and after delivery. An estimated 500,000 pregnancies within the US yearly will end in girls who’ve or may have psychiatric sickness throughout being pregnant.

The potential longitudinal observational cohort examine, entitled “Optimizing Medication Management for Mothers with Depression (OPTI-MOM),” included 88 pregnant girls. They accomplished assessments each 4 weeks from examine entry till supply and at six and 14 weeks postpartum.

Participants had been enrolled at city educational medical facilities together with Northwestern University Feinberg School of Medicine, University of Texas-Galveston, University of Pittsburgh and a rural well being heart (Marshfield Clinic Health System in Wisconsin).

The examine was a collaboration with the University of Pittsburgh, Magee Women’s Hospital; The Ohio State University Wexner Medical Center; and the University of Texas Medical Branch.

Source: Eurekalert



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